Edrophonium

Chemical formula: C₁₀H₁₆NO+  Molecular mass: 166.24 g/mol  PubChem compound: 3202

Active ingredient description

Edrophonium is a reversible acetylcholinesterase inhibitor with rapid onset and short duration of action resulting in an increase of acetylcholine in the neuromuscular junction (NMJ). For many years, edrophonium was FDA-approved to be utilized to diagnose MG.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
V04CX07 V Various → V04 Diagnostic agents → V04C Other diagnostic agents → V04CX Other diagnostic agents
Discover more medicines within V04CX07

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
EDROPHONIUM Ampoules Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 312-48-1
DrugBank Drug: DB01010
PubChem Compound: 3202
RxNorm Ingredient: 3752
SNOMED-CT Concept: 373342004
Edrophonium (substance)
UNII Identifier: 70FP3JLY7N
EDROPHONIUM

Medicines

Edrophonium is an active ingredient of these brands:

Estonia (EE)

Japan (JP)

Spain (ES)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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