Enoximone

Chemical formula: C₁₂H₁₂N₂O₂S  Molecular mass: 248.301 g/mol  PubChem compound: 53708

Pharmacodynamic properties

Enoximone, an imidazolone, has both positive inotropic and vasolidator properties, inhibiting cardiac phosphodiesterase III with an increase in cAMP.

Pharmacokinetic properties

Enoximone half-life ranged from 3 to 8 hours for enoximone and 6-11 hours for the sulphoxide.

0.45% of the intact drug was recovered from the urine and 74% of the metabolite, which is pharmacologically active.

Preclinical safety data

Not applicable.

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