Coagulation factor VIIa Other names: Proconvertin Eptacog alfa

Active ingredient description

Pharmacological doses of rFVIIa activate factor X directly on the surface of activated platelets, localized to the site of injury, independently of tissue factor. This results in the conversion of prothrombin into large amounts of thrombin independently of tissue factor.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
B02BD08 Eptacog alfa (activated) B Blood and blood forming organs → B02 Antihemorrhagics → B02B Vitamin K and other hemostatics → B02BD Blood coagulation factors
Discover more medicines within B02BD08

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
NOVOSEVEN Powder and solvent for solution for injection European Medicines Agency (EU) MPI, EU: SmPC

External identifiers

CAS Substance: 102786-61-8
DrugBank Drug: DB00036
KEGG Drug: D00172
RxNorm Ingredient: 253149
SNOMED-CT Concept: 116066006
Eptacog alfa (substance)
SNOMED-CT Concept: 425337007
Eptacog alfa (substance)
UNII Identifier: AC71R787OV
COAGULATION FACTOR VIIA RECOMBINANT HUMAN

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