Chemical formula: C₁₉H₂₃N₃O₂ Molecular mass: 325.405 g/mol PubChem compound: 443884
Ergometrine produces sustained tonic uterine contraction via agonist or partial agonist effects at myometrial 5-HT2 receptors and alpha-adrenergic receptors. Both upper and lower uterine segments are stimulated to contract in a tetanic manner.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| G02AB03 | Ergometrine | G Genito urinary system and sex hormones → G02 Other gynecologicals → G02A Oxytocics → G02AB Ergot alkaloids |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| ERGOMETRINE Injection | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Ergometrine is an active ingredient of these brands:
Hong Kong (HK)
Ireland (IE)
Malta (MT)
New Zealand (NZ)
Nigeria (NG)
Singapore (SG)
South Africa (ZA)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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