Chemical formula: C₃₃H₃₅N₅O₅ Molecular mass: 581.662 g/mol PubChem compound: 8223
Ergotamine interacts in the following cases:
Ergotamine is contraindicated during pregnancy because it has oxytocic and vasoconstrictor effects on the placenta and umbilical cord.
At high oral doses, ergotamine induced fetal retardation in experimental animals. The observation has been attributed to reduced uteroplacental blood flow.
Women with the potential to become pregnant must use effective birth control throughout the treatment period.
Ergotamine and caffeine are excreted in breast milk. Ergotamine may cause symptoms of vomiting, diarrhoea, weak pulse and unstable blood pressure in infants. Ergotamine is thus contraindicated in nursing mothers.
Patients experiencing dizziness, visual disturbance or impaired reactions, should not drive or operate machinery.
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