Erythromycin

Chemical formula: C₃₇H₆₇NO₁₃  Molecular mass: 733.927 g/mol  PubChem compound: 12560

Therapeutic indications

Erythromycin is indicated for:

Upper respiratory tract infections

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Tonsillitis, peritonsillar abscess, pharyngitis, laryngitis, sinusitis, secondary infections in influenza and common colds.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Lower respiratory tract infections

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Tracheitis, acute and chronic bronchitis, pneumonia (lobar pneumonia, bronchopneumonia, primary atypical pneumonia), bronchiectasis, Legionnaire’s disease.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Ear infection

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Otitis media and otitis externa, mastoiditis.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Oral infections

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Gingivitis, Vincent’s angina.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Blepharitis

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Blepharitis and additionally Erythromycin susceptible species

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Skin and soft tissue infections

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Boils and carbuncles, paronychia, abscesses, pustular acne, impetigo, cellulitis, erysipelas.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Cholecystitis, staphylococcal enterocolitis

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

at least one of
Cholecystitis and additionally Erythromycin susceptible species

Staphylococcal enterocolitis

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Prophylaxis of pre- and post- operative trauma, burns, rheumatic fever

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Preventive procedure and additionally at least one of
Traumatic injury
Burn
Rheumatic fever

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Osteomyelitis, urethritis, gonorrhoea, syphilis, lymphogranuloma venereum, diphtheria, prostatitis, scarlet fever, pertussis

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

at least one of
at least one of
Osteomyelitis
Urethritis
Nicholas Favre disease
Prostatitis
and additionally Erythromycin susceptible species

Diphtheria caused by Corynebacterium diphtheriae
Scarlet fever
Syphilis
Gonorrhea
Pertussis

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Urogenital infections caused by Chlamydia trachomatis, severe gastroenteritis due to Campylobacter jejuni

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

at least one of
Bacterial urogenital infection and additionally Chlamydia trachomatis

Gastroenteritis and additionally Campylobacter jejuni

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Acne vulgaris

Population group: only adolescents (12 years - 18 years old) , adults (18 - 65 years old)

Acne

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Erythromycin is contraindicated in the following cases:

Ergotamine, dihydroergotamine

at least one of
Ergotamine
Dihydroergotamine

Tolterodine, mizolastine, amisulpride, astemizole, terfenadine, domperidone, cisapride, pimozide, disopyramide

at least one of
Tolterodine
Mizolastine
Amisulpride
Astemizole
Terfenadine
Domperidone
Cisapride
Pimozide
Disopyramide

Hypersensitivity to erythromycin

Allergy to erythromycin

Drugs which can cause prolongation of the QT interval

Drugs prolonging QT interval

Simvastatin, atorvastatin, lovastatin

at least one of
Simvastatin
Atorvastatin
Lovastatin

QT interval prolongation, hypokalemia, hypomagnesaemia, ventricular arrhythmias, severe decompensated heart failure (NYHA IV)

at least one of
Long QT syndrome
Prolonged QT interval
Ventricular arrhythmia
Heart failure New York Heart Assosiation Class IV
Hypokalemia
Hypomagnesaemia

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