Fampridine Other names: 4-Aminopyridine 4-AP Dalfampridine

Chemical formula: Câ‚…H₆Nâ‚‚  Molecular mass: 94.115 g/mol  PubChem compound: 1727

Active ingredient description

Fampridine is a potassium channel blocker. By blocking potassium channels, fampridine reduces the leakage of ionic current through these channels, thereby prolonging repolarization and thus enhancing action potential formation in demyelinated axons and neurological function.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N07XX07 Fampridine N Nervous system → N07 Other nervous system drugs → N07X Other nervous system drugs → N07XX Other nervous system drugs
Discover more medicines within N07XX07

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
FAMPYRA Prolonged-release tablets European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 902-55-
DrugBank Drug: DB06637
KEGG Drug: D04127
PubChem Compound: 1727
RxNorm Ingredient: 897018
SNOMED-CT Concept: 80994002
Fampridine (substance)
UNII Identifier: BH3B64OKL9
DALFAMPRIDINE

Medicines

Fampridine is an active ingredient of these brands:

United States (US)

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Ireland (IE)

Israel (IL)

Lithuania (LT)

Netherlands (NL)

New Zealand (NZ)

Poland (PL)

Romania (RO)

South Africa (ZA)

Spain (ES)

Turkey (TR)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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