Flecainide

Chemical formula: C₁₇H₂₀F₆N₂O₃  Molecular mass: 414.343 g/mol  PubChem compound: 3356

Therapeutic indications

Flecainide is indicated for:

Supraventricular arrhythmia, re-entrant atrioventricular node tachycardia, Wolff-Parkinson-White pattern

Population group: only adolescents (12 years - 18 years old) , adults (18 - 65 years old)

Treatment of AV nodal reciprocating tachycardia; arrhythmias associated with Wolff-Parkinson-White Syndrome and similar conditions with accessory pathways, when other treatment has been ineffective.

Treatment of paroxysmal atrial arrhythmias (atrial fibrillation, atrial flutter and atrial tachycardia) in patients with disabling symptoms after conversion provided that there is definite need for treatment on the basis of severity of clinical symptoms, when other treatment has been ineffective. Structural heart disease and/or impaired left ventricular function should be excluded because of the increased risk for pro-arrhythmic effects.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Supraventricular arrhythmia, re-entrant atrioventricular node tachycardia, Wolff-Parkinson-White pattern

Population group: only elderly (65 years old or older)

Treatment of AV nodal reciprocating tachycardia; arrhythmias associated with Wolff-Parkinson-White Syndrome and similar conditions with accessory pathways, when other treatment has been ineffective.

Treatment of paroxysmal atrial arrhythmias (atrial fibrillation, atrial flutter and atrial tachycardia) in patients with disabling symptoms after conversion provided that there is definite need for treatment on the basis of severity of clinical symptoms, when other treatment has been ineffective. Structural heart disease and/or impaired left ventricular function should be excluded because of the increased risk for pro-arrhythmic effects.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Paroxysmal ventricular arrhythmia

Population group: only adolescents (12 years - 18 years old) , adults (18 - 65 years old)

Treatment of severe symptomatic and life-threatening paroxysmal ventricular arrhythmia which has failed to respond to other forms of therapy or where other treatments have not been tolerated.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Flecainide is contraindicated in the following cases:

Brugada syndrome

Brugada syndrome

Sinus node dysfunction

Coronary sinus rhythm disorder

Second degree atrioventricular block, complete atrioventricular block

at least one of
Second degree atrioventricular block
Complete atrioventricular block

Bundle branch block

Bundle branch block

Atrial septal defect

Atrial septal defect

Cardiac failure

Cardiac failure

Get recommendations

Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

Ask the Reasoner

Related medicines

© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.