Florbetapir ¹⁸F Other names: Florbetapir fluorine 18 Florbetapir (18F) Florbetapir F-18

Chemical formula: C₂₀H₂₅FN₂O₃  Molecular mass: 359.432 g/mol  PubChem compound: 24822371

Active ingredient description

Florbetapir ¹⁸F binds to β-amyloid plaques and the ¹⁸F isotope produces a positron signal that is detected by a PET scanner. Florbetapir ¹⁸F is indicated for Positron Emission Tomography (PET) imaging of the brain to estimate β-amyloid neuritic plaque density in adult patients with cognitive impairment who are being evaluated for Alzheimer’s Disease (AD) and other causes of cognitive decline.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
V09AX05 V Various → V09 Diagnostic radiopharmaceuticals → V09A Central nervous system → V09AX Other central nervous system diagnostic radiopharmaceuticals
Discover more medicines within V09AX05

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
AMYVID Solution for injection FDA, National Drug Code (US) MPI, US: SPL/PLR

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 956103-76-7
DrugBank Drug: DB09149
KEGG Drug: D09617
PubChem Compound: 24822371
RxNorm Ingredient: 1427224
SNOMED-CT Concept: 456995000
Florbetapir (18-F) (substance)
UNII Identifier: 6867Q6IKOD
FLORBETAPIR
UNII Identifier: 6W15Z5R0RU
FLORBETAPIR F-18

Medicines

Florbetapir ¹⁸F is an active ingredient of these brands:

United States (US)

Austria (AT)

Croatia (HR)

Estonia (EE)

Ireland (IE)

Japan (JP)

Lithuania (LT)

Poland (PL)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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