Fludrocortisone Other names: Fluorohydrocortisone

Chemical formula: C₂₁H₂₉FO₅  Molecular mass: 380.45 g/mol  PubChem compound: 31378

Active ingredient description

Fludrocortisone, in very small doses, maintains life in adrenalectomised animals, enhances the deposition of liver glycogen and produces thymic involution, eosinopenia, retention of sodium and increased urinary excretion of potassium.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
H02AA02 Fludrocortisone H Systemic hormonal preparations, excl. Sex hormones and insulins → H02 Corticosteroids for systemic use → H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN → H02AA Mineralocorticoids
Discover more medicines within H02AA02

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
FLUDROCORTISONE ACETATE Tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 127-31-1
CAS Substance: 514-36-3
DrugBank Drug: DB00687
KEGG Drug: D07967
PubChem Compound: 31378
RxNorm Ingredient: 4452
SNOMED-CT Concept: 116586002
Fludrocortisone (substance)
UNII Identifier: U0476M545B
FLUDROCORTISONE

Medicines

Fludrocortisone is an active ingredient of these brands:

Australia (AU)

Austria (AT)

Brazil (BR)

  • FLORINEFE as FLUDROCORTISONE ACETATE

  • (combination) PANOTIL as FLUDROCORTISONE ACETATE

Canada (CA)

Croatia (HR)

  • ZONTA as FLUDROCORTISONE ACETATE

Cyprus (CY)

Estonia (EE)

Finland (FI)

France (FR)

Hong Kong (HK)

  • FLORINEF as FLUDROCORTISONE ACETATE

  • (combination) PAROTICIN as FLUDROCORTISONE ACETATE

Japan (JP)

Lithuania (LT)

Malta (MT)

Netherlands (NL)

New Zealand (NZ)

Poland (PL)

Romania (RO)

Singapore (SG)

Spain (ES)

Turkey (TR)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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