Fosfomycin

Chemical formula: C₃H₇Oâ‚„P  Molecular mass: 138.059 g/mol  PubChem compound: 446987

Active ingredient description

Fosfomycin exerts a bactericidal effect on proliferating pathogens by preventing the enzymatic synthesis of the bacterial cell wall. Fosfomycin inhibits the first stage of intracellular bacterial cell wall synthesis by blocking peptidoglycan synthesis.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
J01XX01 Fosfomycin J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01X Other antibacterials → J01XX Other antibacterials
Discover more medicines within J01XX01
S02AA17 S Sensory organs → S02 Otologicals → S02A Antiinfectives → S02AA Antiinfectives
Discover more medicines within S02AA17

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
MONUROL Granules for oral solution FDA, National Drug Code (US) MPI, US: SPL/Old
FOMICYT Powder for solution for infusion Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
MONURIL Granules for oral solution Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 23155-02-4
DrugBank Drug: DB00828
KEGG Drug: D04253
PubChem Compound: 446987
RxNorm Ingredient: 4550
SNOMED-CT Concept: 372534005
Fosfomycin (substance)
UNII Identifier: 2N81MY12TE
FOSFOMYCIN

Medicines

Fosfomycin is an active ingredient of these brands:

United States (US)

  • MONUROL as FOSFOMYCIN TROMETHAMINE

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

Ecuador (EC)

Estonia (EE)

France (FR)

Hong Kong (HK)

  • MONUROL as FOSFOMYCIN TROMETHAMINE

Ireland (IE)

Israel (IL)

  • MONUROL as FOSFOMYCIN TROMETHAMINE

Italy (IT)

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

  • UROFOS as FOSFOMYCIN TROMETHAMINE

Poland (PL)

Romania (RO)

Singapore (SG)

  • MONUROL as FOSFOMYCIN TROMETHAMINE

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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