Chemical formula: C₃₀H₄₆NO₇P Molecular mass: 563.672 g/mol PubChem compound: 55891
Fosinopril is the pro-drug (ester) of the long acting active ACE inhibitor fosinoprilat. After oral administration fosinopril is quickly and fully metabolised to the active fosinoprilat. Fosinopril contains a phosphinic group capable of a specific binding to the active site of the angiotensin converting enzyme, preventing the conversion of angiotensin I in angiotensin II.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C09AA09 | Fosinopril | C Cardiovascular system → C09 Agents acting on the renin-angiotensin system → C09A ACE inhibitors, plain → C09AA ACE inhibitors, plain |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| FOSINOPRIL SODIUM Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Fosinopril is an active ingredient of these brands:
Australia (AU)Estonia (EE)
Germany (DE)
Italy (IT)Lithuania (LT)Romania (RO)
Spain (ES)
Turkey (TR)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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