Frovatriptan

Chemical formula: C₁₄H₁₇N₃O  Molecular mass: 243.304 g/mol  PubChem compound: 77992

Therapeutic indications

Frovatriptan is indicated for:

Migraine

Population group: only adults (18 years old or older)

Acute treatment of the headache phase of migraine attacks with or without aura.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Frovatriptan is contraindicated in the following cases:

Severe hepatic impairment

Hepatic failure stage IV

Myocardial infarction, ischaemic heart disease, coronary vasospasm, peripheral vascular disease

at least one of
Past history of myocardial infarction
Myocardial infarction
Ischemic heart disease
Coronary artery spasm
Peripheral vascular disease
History of peripheral vascular disease
Coronary arteriosclerosis
At risk of coronary heart disease
Heavy smoker (over 20 per day)

Moderately severe hypertension, severe hypertension, uncontrolled mild hypertension

Hypertension

Previous cerebrovascular accident (CVA), previous transient ischaemic attack (TIA)

at least one of
CVA - Cerebrovascular accident
H/O: CVA
Temporary cerebral vascular dysfunction
History of transient ischemic attack

Ergotamine, 5-hydroxytryptamine receptor agonists (5-ΗΤ1)

at least one of
Ergotamine
Selective serotonin (5HT1) agonists

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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