Chemical formula: C₁₇H₂₁NO₃ Molecular mass: 287.354 g/mol PubChem compound: 9651
Galantamine, a tertiary alkaloid is a selective, competitive and reversible inhibitor of acetylcholinesterase. In addition, galantamine enhances the intrinsic action of acetylcholine on nicotinic receptors, probably through binding to an allosteric site of the receptor. As a consequence, an increased activity in the cholinergic system associated with improved cognitive function can be achieved in patients with dementia of the Alzheimer type.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| N06DA04 | Galantamine | N Nervous system → N06 Psychoanaleptics → N06D Anti-dementia drugs → N06DA Anticholinesterases |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| CONSION XL Prolonged-release capsule, hard | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Galantamine is an active ingredient of these brands:
United States (US)
Austria (AT)
Brazil (BR)Ecuador (EC)
Estonia (EE)Finland (FI)
France (FR)
Germany (DE)
Hong Kong (HK)
Israel (IL)
Japan (JP)
Malta (MT)
Mexico (MX)
Netherlands (NL)
New Zealand (NZ)
Singapore (SG)
South Africa (ZA)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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