Ganciclovir Other names: 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine DHPG

Chemical formula: C₉H₁₃N₅O₄  Molecular mass: 255.231 g/mol  PubChem compound: 3454

Active ingredient description

Ganciclovir, 9-(1,3-dihydroxy-2-propoxymethyl)guanine or DHPG, is a broadspectrum virustatic agent which inhibits the replication of viruses, including viruses of the herpes group, both in vivo and in vitro: herpes simplex types 1 and 2 (HSV), cytomegalovirus (CMV), Epstein-Barr virus (EBV), herpes zoster (HZV).

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
J05AB06 Ganciclovir J Antiinfectives for systemic use → J05 Antivirals for systemic use → J05A Direct acting antivirals → J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
Discover more medicines within J05AB06
S01AD09 Ganciclovir S Sensory organs → S01 Ophthalmologicals → S01A Antiinfectives → S01AD Antivirals
Discover more medicines within S01AD09

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
VIRGAN Eye gel Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
CYTOVENE-IV Solution for injection FDA, National Drug Code (US) MPI, US: SPL/PLR
CYMEVENE Powder for concentrate for solution Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 107910-75-8
CAS Substance: 82410-32-0
DrugBank Drug: DB01004
KEGG Drug: D00333
PubChem Compound: 3454
RxNorm Ingredient: 4678
SNOMED-CT Concept: 372848001
Ganciclovir (substance)
UNII Identifier: P9G3CKZ4P5
GANCICLOVIR

Medicines

Ganciclovir is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

Estonia (EE)

Finland (FI)

France (FR)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

Japan (JP)

Lithuania (LT)

Malta (MT)

Netherlands (NL)

New Zealand (NZ)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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