Gemcitabine Other names: dFdC 2', 2'-difluoro-2'deoxycytidine

Chemical formula: C₉H₁₁F₂N₃O₄  Molecular mass: 263.198 g/mol  PubChem compound: 60750

Therapeutic indications

Gemcitabine is indicated for:

Non-small cell lung cancer (NSCLC)

Population group: only adults (18 years old or older)

Gemcitabine, in combination with cisplatin is indicated as first line treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC). Gemcitabine monotherapy can be considered in elderly patients or those with performance status 2.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Adenocarcinoma of the pancreas

Population group: only adults (18 years old or older)

Gemcitabine is indicated for treatment of patients with locally advanced or metastatic adenocarcinoma of the pancreas.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Breast cancer

Population group: only adults (18 years old or older)

Gemcitabine, in combination with paclitaxel, is indicated for the treatment of patients with unresectable, locally recurrent or metastatic breast cancer who have relapsed following adjuvant/neoadjuvant chemotherapy. Prior chemotherapy should have included an anthracycline unless clinically contraindicated.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Epithelial ovarian carcinoma

Population group: women, only adults (18 years old or older)

Gemcitabine is indicated for the treatment of patients with locally advanced or metastatic epithelial ovarian carcinoma, in combination with carboplatin, in patients with relapsed disease following a recurrence-free interval of at least 6 months after platinum-based, first-line therapy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Bladder cancer

Population group: only adults (18 years old or older)

Gemcitabine is indicated for the treatment of locally advanced or metastatic bladder cancer in combination with cisplatin.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Gemcitabine is contraindicated in the following cases:

Pregnancy

Pregnancy

Lactation

Lactation

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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