Chemical formula: C₁₈H₂₄N₄O Molecular mass: 312.417 g/mol PubChem compound: 5284566
Granisetron is a potent anti-emetic and highly selective antagonist of 5-hydroxytryptamine (5HT3 receptors). Pharmacological studies have demonstrated that granisetron is effective against nausea and vomiting as a result of cytostatic therapy.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| A04AA02 | Granisetron | A Alimentary tract and metabolism → A04 Antiemetics and antinauseants → A04A Antiemetics and antinauseants → A04AA Serotonin (5HT3) antagonists |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| GRANISETRON Concentrate for solution for injection or infusion | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| SANCUSO Transdermal patch | European Medicines Agency (EU) | MPI, EU: SmPC | |
| GRANISETRON Film-coated tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Granisetron is an active ingredient of these brands:
Australia (AU)
Croatia (HR)Ecuador (EC)
Japan (JP)
Lithuania (LT)Mexico (MX)
New Zealand (NZ)
Poland (PL)South Africa (ZA)Spain (ES)
Tunisia (TN)Turkey (TR)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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