Chemical formula: C₁₀H₁₄O₄ Molecular mass: 198.216 g/mol PubChem compound: 3516
Guaifenesin interacts in the following cases:
Caution in administration of guaifenesin should be exercised in severe renal impairment.
Caution in administration of guaifenesin should be exercised in severe hepatic impairment.
The concomitant use of guaifenesin with cough suppressants is not recommended.
There are no or limited amount of data from the use of guaifenesin in pregnant women. Animal studies are insufficient with respect to reproductive toxicity. Guaifenesin is not recommended during pregnancy and in women of childbearing potential not using contraception.
Guaifenesin is excreted in breast milk in small amounts. There is insufficient information on the effects of guaifenesin in newborns/infants. A decision must be made whether to discontinue breast-feeding or to discontinue/abstain from guaifenesin therapy, taking into account the benefit of breast feeding for the child and the benefit of therapy for the woman.
Guaifenesin has no or negligible influence on the ability to drive and use machines.
The following side effects may be associated with the use of guaifenesin:
Immune System Disorders: Hypersensitivity reactions including pruritus and urticaria, rash (frequency – not known).
Gastrointestinal disorders: Abdominal pain upper, diarrhoea, nausea, vomiting (frequency – not known).
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