Hyaluronidase

Active ingredient description

Hyaluronidase is an enzyme that has a temporary and reversible depolymerising effect on the polysaccharide hyaluronic acid, which is present in the intercellular matrix of connective tissue.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
B06AA03 Hyaluronidase B Blood and blood forming organs → B06 Other hematological agents → B06A Other hematological agents → B06AA Enzymes
Discover more medicines within B06AA03

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
HYALASE Powder for solution for injection/infusion Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

External identifiers

CAS Substance: 9001-54-1
DrugBank Drug: DB00070
RxNorm Ingredient: 5464
SNOMED-CT Concept: 387280008
Hyaluronidase (substance)
UNII Identifier: 64R4OHP8T0
HYALURONIDASE (OVINE)
UNII Identifier: 8KOG53Z5EM
HYALURONIDASE (BOVINE)

Medicines

Hyaluronidase is an active ingredient of these brands:

United States (US)

Austria (AT)

Brazil (BR)

  • (combination) HYAX as HYALURONIDASE (BOVINE)
  • (combination) OTO-XILODASE as HYALURONIDASE (BOVINE)
  • (combination) POSTEC as HYALURONIDASE (BOVINE)

Estonia (EE)

Hong Kong (HK)

Israel (IL)

Japan (JP)

  • (combination) DARZQURO as Vorhyaluronidase alfa

Malta (MT)

New Zealand (NZ)

Singapore (SG)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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