Hydroquinidine

Chemical formula: C₂₀H₂₆N₂O₂  Molecular mass: 326.44 g/mol  PubChem compound: 91503

Active ingredient description

Hydroquinidine is a d-rotatory alkaloid derived from cinchiona bark. Hydroquinidine is a pharmaceutical agent that acts as a class I antiarrhythmic agent (Ia) in the heart. Hydroquinidine causes increased action potential duration, as well as a prolonged QT interval. Like all other class I antiarrhythmic agents, hydroquinidine primarily works by blocking the fast inward sodium current (INa). Hydroquinidine is also used for the treatment of Malaria.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
C01BA13 C Cardiovascular system → C01 Cardiac therapy → C01B Antiarrhythmics, class I and III → C01BA Antiarrhythmics, class Ia
Discover more medicines within C01BA13

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 56-54-2
DrugBank Drug: DB15300
KEGG Drug: D08048
PubChem Compound: 91503
RxNorm Ingredient: 9068
SNOMED-CT Concept: 765387007
Hydroquinidine (substance)
UNII Identifier: 8P68XPY4HG
HYDROQUINIDINE

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