Ibandronic acid

Also known as: Ibandronate sodium

Active ingredient description

Ibandronic acid belongs to the bisphosphonate group of compounds which act specifically on bone. Their selective action on bone tissue is based on the high affinity of bisphosphonates for bone mineral. Bisphosphonates act by inhibiting osteoclast activity, although the precise mechanism is still not clear. In vivo, ibandronic acid prevents experimentally-induced bone destruction caused by cessation of gonadal function, retinoids, tumours or tumour extracts.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Ibandronic acid
M Musculo-skeletal system → M05 Drugs for treatment of bone diseases → M05B Drugs affecting bone structure and mineralization → M05BA Bisphosphonates
Discover more medicines within M05BA06

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Summary of Product Characteristics (SPC)
Summary of Product Characteristics (SPC)

Medicines

Ibandronic acid is the active ingredient of these drugs:

Drug
Countries

Spain

Ecuador

Brazil

Germany

Estonia Lithuania

Ecuador

South Africa

Australia Austria Ecuador Estonia France

Ecuador

Estonia Ireland Lithuania Poland

Ecuador

South Africa United States

Hong Kong

Germany

South Africa

Austria Brazil Cyprus Ecuador Estonia

Finland

Ecuador

Ecuador

Estonia

Ecuador

Austria Cyprus Estonia Ireland Lithuania

Ecuador

Brazil

Brazil

Ecuador

Ecuador

Ecuador

Poland

Austria Estonia Poland

Estonia

Poland

Lithuania Poland

Brazil

Ecuador Estonia Lithuania Poland

Brazil

Ecuador

Brazil

Austria

South Africa

United Kingdom

Ecuador

Ecuador

Brazil

Ibandronic acid is also found within below combination drugs:

ACIBAN D

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₉H₂₃NO₇P₂
Molecular mass: 319.229 g/mol

External identifiers

CAS Substance: 114084-78-5
DrugBank Drug: DB00710
PubChem Compound: 60852
RxNorm Ingredient: 115265
SNOMED-CT Concept: 420936009
Ibandronic acid (substance)
UNII Identifier: UMD7G2653W
IBANDRONIC ACID