Imlifidase

Therapeutic indications

Imlifidase is indicated for:

Desensitisation treatment of highly sensitised adult kidney transplant patients

Imlifidase is indicated for desensitisation treatment of highly sensitised adult kidney transplant patients with positive crossmatch against an available deceased donor. The use of imlifidase should be reserved for patients unlikely to be transplanted under the available kidney allocation system including prioritisation programmes for highly sensitised patients.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Imlifidase is contraindicated in the following cases:

Ongoing serious infection

Persistent infection

Thrombotic thrombocytopenic purpura (TTP)

Thrombotic thrombocytopenic purpura

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