Indium ¹¹¹In oxyquinoline

Molecular mass: 543.364 g/mol  PubChem compound: 119117

Active ingredient description

Indium forms a saturated (1:3) complex with oxyquinoline. The complex is neutral and lipid-soluble, which enables it to penetrate the cell membrane. It is thought likely that the mechanism of labeling cells with indium In-111 oxyquinoline involves an exchange reaction between the oxyquinoline carrier and subcellular components which chelate indium more strongly than oxyquinoline.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
V09HB01 Indium (111In) oxinate labelled cells V Various → V09 Diagnostic radiopharmaceuticals → V09H Inflammation and infection detection → V09HB Indium (111In) compounds
Discover more medicines within V09HB01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
INDIUM IN-111 OXYQUINOLINE Solution for injection FDA, National Drug Code (US) MPI, US: SPL/Old

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 65389-08-4
DrugBank Drug: DB09473
KEGG Drug: D04526
PubChem Compound: 119117
RxNorm Ingredient: 1314372
SNOMED-CT Concept: 395747004
Indium (111-In) oxine (substance)
UNII Identifier: LGX9OL562T
INDIUM IN-111 OXYQUINOLINE

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