Isavuconazole

Chemical formula: C₂₂H₁₇F₂N₅OS  Molecular mass: 437.47 g/mol 

Therapeutic indications

Isavuconazole is indicated for:

Invasive aspergillosis, mucormycosis

Population group: only adults (18 years old or older)

Isavuconazole is indicated in adults for the treatment of:

  • invasive aspergillosis
  • mucormycosis in patients for whom amphotericin B is inappropriate

Consideration should be given to official guidance on the appropriate use of antifungal agents.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Isavuconazole is contraindicated in the following cases:

Ketoconazole

Ketoconazole

Ritonavir

Ritonavir

Moderate and strong CYP3A4/5 inducers

at least one of
CYP3A4 inducers
Cytochrome P-450 CYP3A5 moderate inducers
Cytochrome P-450 CYP3A5 strong inducers

Familial short QT syndrome

Short QT syndrome

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