Chemical formula: C₉H₇Cl₂N₅ Molecular mass: 256.091 g/mol PubChem compound: 3878
Lamotrigine is a use and voltage dependent blocker of voltage gated sodium channels. It inhibits sustained repetitive firing of neurons and inhibits release of glutamate (the neurotransmitter which plays a key role in the generation of epileptic seizures).
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| N03AX09 | Lamotrigine | N Nervous system → N03 Antiepileptics → N03A Antiepileptics → N03AX Other antiepileptics |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| LAMOTRIGINE / MYLAN Dispersible tablets | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Lamotrigine is an active ingredient of these brands:
Canada (CA)Estonia (EE)Finland (FI)France (FR)Germany (DE)Japan (JP)Lithuania (LT)Malta (MT)Mexico (MX)Netherlands (NL)South Africa (ZA)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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