Leflunomide C₁₂H₉F₃N₂O₂
Active ingredient description
Leflunomide is a disease-modifying anti-rheumatic agent with antiproliferative properties. A771726, the active metabolite of leflunomide, inhibits the human enzyme dihydroorotate dehydrogenase (DHODH) and exhibits antiproliferative activity.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
Product monographs
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
Structural formula
Chemical formula: C₁₂H₉F₃N₂O₂
Molecular mass: 270.207 g/mol
External identifiers
Medicines
Leflunomide is an active ingredient of these brands:
United States (US)
Austria (AT)
Canada (CA)
Ecuador (EC)
Finland (FI)
France (FR)
Italy (IT)
Japan (JP)
Mexico (MX)
Netherlands (NL)
New Zealand (NZ)
Poland (PL)
Romania (RO)
Singapore (SG)
Spain (ES)
United Kingdom (UK)
While we strive to include the brand names of medicines across all countries, our index remains incomplete. Therefore, it is possible that this medicine may also be marketed under different names in other countries.
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