Chemical formula: C₁₃H₁₀ClN₃O₄S₂ Molecular mass: 371.81 g/mol PubChem compound: 54690031
Lornoxicam is a non-steroidal anti-inflammatory drug with analgesic properties and belongs to the class of oxicams. Lornoxicams mode of action is mainly related to the inhibition of the prostaglandin synthesis (inhibition of the cyclooxygenase enzyme) leading to desensitisation of peripheral nociceptors and consequently inhibition of inflammation. A central effect on nociception, which seems to be independent of anti-inflammatory effects has also been suggested.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| M01AC05 | Lornoxicam | M Musculo-skeletal system → M01 Antiinflammatory and antirheumatic products → M01A Antiinflammatory and antirheumatic products, non-steroids → M01AC Oxicams |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| XEFO Powder and solvent for solution for injection | MPI, EU: SmPC | ||
| XEFO Film-coated tablets | Health Products Regulatory Authority (IE) | MPI, EU: SmPC |
Lornoxicam is an active ingredient of these brands:
Austria (AT)Brazil (BR)Ecuador (EC)Estonia (EE)Israel (IL)Japan (JP)Lithuania (LT)Poland (PL)Romania (RO)South Africa (ZA)Spain (ES)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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