Loxapine

Chemical formula: C₁₈H₁₈ClN₃O  Molecular mass: 327.808 g/mol  PubChem compound: 3964

Active ingredient description

Loxapine binds with noradrenergic, histaminergic, and cholinergic receptors, and its interaction with these systems may influence the spectrum of its pharmacological effects. Loxapine is indicated for the rapid control of mild-to-moderate agitation in adult patients with schizophrenia or bipolar disorder.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N05AH01 Loxapine N Nervous system → N05 Psycholeptics → N05A Antipsychotics → N05AH Diazepines, oxazepines and thiazepines
Discover more medicines within N05AH01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
ADASUVE Inhalation powder European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 1977-10-2
DrugBank Drug: DB00408
KEGG Drug: D02340
PubChem Compound: 3964
RxNorm Ingredient: 6475
SNOMED-CT Concept: 372789006
Loxapine (substance)
UNII Identifier: LER583670J
LOXAPINE

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