Macimorelin

Chemical formula: C₂₆H₃₀N₆O₃  Molecular mass: 474.565 g/mol 

Active ingredient description

Macimorelin is an orally available peptidomimetic with growth hormone (GH) secretagogue activity similar to ghrelin. Macimorelin stimulates GH release by activating growth hormone secretagogue receptors (GHSR) present in the pituitary and hypothalamus.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
V04CD06 V Various → V04 Diagnostic agents → V04C Other diagnostic agents → V04CD Tests for pituitary function
Discover more medicines within V04CD06

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
GHRYVELIN Granules for oral suspension European Medicines Agency (EU) MPI, EU: SmPC
MACRILEN Granule for solution FDA, National Drug Code (US) MPI, US: SPL/PLR

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 381231-18-1
DrugBank Drug: DB13074
KEGG Drug: D10563
RxNorm Ingredient: 1999420
SNOMED-CT Concept: 781246008
Macimorelin (substance)
UNII Identifier: 8680B21W73
MACIMORELIN

Medicines

Macimorelin is an active ingredient of these brands:

United States (US)

Austria (AT)

Croatia (HR)

Estonia (EE)

France (FR)

Ireland (IE)

Italy (IT)

Lithuania (LT)

Poland (PL)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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