Maprotiline Other names: Maprotiline hydrochloride

Chemical formula: C₂₀H₂₃N  Molecular mass: 277.403 g/mol  PubChem compound: 4011

Active ingredient description

Maprotiline is a tetracyclic antidepressant, psychoanaleptics, non-selective mono-amine reuptake inhibitor, which shares a number of basic therapeutic properties with the tricyclic antidepressants. It displays a well-balanced spectrum of action, brightening mood and alleviating anxiety, agitation and psychomotor retardation. In masked depression, it can exert a favourable influence on somatic symptoms.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N06AA21 Maprotiline N Nervous system → N06 Psychoanaleptics → N06A Antidepressants → N06AA Non-selective monoamine reuptake inhibitors
Discover more medicines within N06AA21

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
LUDIOMIL Film coated tablet Medicines and Medical Devices Safety Authority (NZ) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 10262-69-8
CAS Substance: 10347-81-6
DrugBank Drug: DB00934
KEGG Drug: D02566
PubChem Compound: 4011
RxNorm Ingredient: 6646
SNOMED-CT Concept: 387180003
Maprotiline (substance)
UNII Identifier: 2U1W68TROF
MAPROTILINE

Medicines

Maprotiline is an active ingredient of these brands:

Austria (AT)

Croatia (HR)

Cyprus (CY)

France (FR)

Israel (IL)

  • MELODIL as MAPROTILINE HYDROCHLORIDE

Japan (JP)

Poland (PL)

South Africa (ZA)

Spain (ES)

Turkey (TR)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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