Methyl aminolevulinate

Chemical formula: C₆H₁₁NO₃  Molecular mass: 145.156 g/mol  PubChem compound: 157922

Therapeutic indications

Methyl aminolevulinate is indicated for:

Photodynamic therapy in actinic keratoses (AK)

Population group: only adults (18 years old or older)

Treatment of thin or non-hyperkeratotic and non-pigmented actinic keratoses on the face and scalp when other therapies are considered less appropriate.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Photodynamic therapy in superficial and/or nodular basal cell carcinoma

Population group: only adults (18 years old or older)

Only for treatment of superficial and/or nodular basal cell carcinoma unsuitable for other available therapies due to possible treatment related morbidity and poor cosmetic outcome; such as lesions on the mid-face or ears, lesions on severely sun damaged skin, large lesions, or recurrent lesions.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Photodynamic therapy in squamous cell carcinoma in situ (Bowen´s disease)

Population group: only adults (18 years old or older)

Treatment of squamous cell carcinoma in situ (Bowen´s disease) when surgical excision is considered less appropriate.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Methyl aminolevulinate is contraindicated in the following cases:

Porphyria

Porphyria

Morpheaform basal cell carcinoma

Basal cell carcinoma of skin and additionally † Basal cell carcinoma - morphoeic

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