Midodrine

Chemical formula: C₁₂H₁₈N₂O₄  Molecular mass: 254.282 g/mol  PubChem compound: 4195

Active ingredient description

Midodrine is the rapidly absorbed pro-drug of the pharmacologically active constituent desglymidodrine. Desglymidodrine is a sympathicomimetic with a direct and selective effect on the peripheral α1-adrenergic receptors. This α1-stimulative effect induces vasoconstriction of the venous system.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
C01CA17 Midodrine C Cardiovascular system → C01 Cardiac therapy → C01C Cardiac stimulants excl. cardiac glycosides → C01CA Adrenergic and dopaminergic agents
Discover more medicines within C01CA17

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
GUTRON Tablets European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 3092-17-9
CAS Substance: 42794-76-3
DrugBank Drug: DB00211
KEGG Drug: D08220
PubChem Compound: 4195
RxNorm Ingredient: 6963
SNOMED-CT Concept: 372504000
Midodrine (substance)
UNII Identifier: 6YE7PBM15H
MIDODRINE

Medicines

Midodrine is an active ingredient of these brands:

Austria (AT)

  • GUTRON as MIDODRINE HYDROCHLORIDE

Estonia (EE)

  • GUTRON as MIDODRINE HYDROCHLORIDE

Finland (FI)

France (FR)

  • GUTRON as MIDODRINE HYDROCHLORIDE

Germany (DE)

  • GUTRON as MIDODRINE HYDROCHLORIDE

Hong Kong (HK)

  • GUTRON as MIDODRINE HYDROCHLORIDE

Ireland (IE)

  • MIDON as MIDODRINE HYDROCHLORIDE

Japan (JP)

Netherlands (NL)

  • GUTRON as MIDODRINE HYDROCHLORIDE

New Zealand (NZ)

  • GUTRON as MIDODRINE HYDROCHLORIDE

Poland (PL)

  • GUTRON as MIDODRINE HYDROCHLORIDE

Romania (RO)

  • GUTRON as MIDODRINE HYDROCHLORIDE

Singapore (SG)

  • GUTRON as MIDODRINE HYDROCHLORIDE

Spain (ES)

  • GUTRON as MIDODRINE HYDROCHLORIDE

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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