Mifamurtide

Chemical formula: C₅₉H₁₀₉N₆O₁₉P  Molecular mass: 1,277.515 g/mol 

Active ingredient description

Mifamurtide (MTP-PE) is a fully synthetic derivative of muramyl dipeptide (MDP). MTP-PE is a potent activator of monocytes and macrophages. The exact mechanism by which mifamurtide activation of monocytes and macrophages leads to anti-tumour activity in animals and humans is not yet known.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
L03AX15 Mifamurtide L Antineoplastic and immunomodulating agents → L03 Immunostimulants → L03A Immunostimulants → L03AX Other immunostimulants
Discover more medicines within L03AX15

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
MEPACT Powder for concentrate for dispersion for infusion European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 83461-56-7
DrugBank Drug: DB13615
SNOMED-CT Concept: 710284002
Mifamurtide (substance)
UNII Identifier: 1LM890Q4FY
MIFAMURTIDE

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