Milrinone

Chemical formula: C₁₂H₉N₃O  Molecular mass: 211.219 g/mol  PubChem compound: 4197

Active ingredient description

Milrinone is a positive inotrope and vasodilator, with little chronotropic activity. It also improves left ventricular diastolic relaxation. It is a selective inhibitor of peak III phosphodiesterase isoenzyme in cardiac and vascular muscle. It produces slight enhancement of A-V node conduction, but no other significant electrophysiological effects.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
C01CE02 Milrinone C Cardiovascular system → C01 Cardiac therapy → C01C Cardiac stimulants excl. cardiac glycosides → C01CE Phosphodiesterase inhibitors
Discover more medicines within C01CE02

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
MILNIRONE Solution for injection / infusion Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 78415-72-2
DrugBank Drug: DB00235
KEGG Drug: D00417
PubChem Compound: 4197
RxNorm Ingredient: 52769
SNOMED-CT Concept: 373441005
Milrinone (substance)
UNII Identifier: JU9YAX04C7
MILRINONE

© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.