Moxifloxacin

Chemical formula: C₂₁H₂₄FN₃O₄  Molecular mass: 401.431 g/mol  PubChem compound: 152946

Therapeutic indications

Moxifloxacin is indicated for:

Community acquired pneumonia (CAP), complicated skin and skin structure infections (cSSSI)

Population group: only adults (18 years old or older)

Moxifloxacin is indicated for the treatment of:

  • Community acquired pneumonia (CAP).
  • Complicated skin and skin structure infections (cSSSI).

Moxifloxacin should be used only when it is considered inappropriate to use antibacterial agents that are commonly recommended for the initial treatment of these infections.

Consideration should be given to official guidance on the appropriate use of antibacterial agents.

Community acquired pneumonia (CAP), complicated skin and skin structure infections (cSSSI)

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Acute exacerbation of chronic bronchitis

Population group: only adults (18 years old or older)

Acute exacerbation of chronic bronchitis

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Acute bacterial sinusitis

Population group: only adults (18 years old or older)

Acute bacterial sinusitis

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Mild to moderate pelvic inflammatory disease

Population group: only adults (18 years old or older)

Infectious disease of abdomen and additionally at least one of
Moxifloxacin susceptible species
Moxifloxacin susceptible species for which acquired resistance may be a problem

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Purulent bacterial conjunctivitis

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Topical treatment of purulent bacterial conjunctivitis, caused by moxifloxacin susceptible strains. Consideration should be given to official guidance on the appropriate use of antibacterial agents.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Moxifloxacin is contraindicated in the following cases:

Pregnancy

Pregnancy

Lactation

Lactation

Prolonged QT interval, congenital or documented acquired QT prolongation, drugs that prolong the QT interval

at least one of
Prolonged QT interval
Long QT syndrome
Drugs prolonging QT interval

Bradycardia

Bradycardia

Hypokalemia

Hypokalemia

Heart failure with reduced left-ventricular ejection fraction

Heart failure with reduced ejection fraction

Impaired liver function (Child Pugh C)

Hepatic failure stage IV

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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