Naftidrofuryl

Chemical formula: C₂₄H₃₃NO₃  Molecular mass: 383.524 g/mol 

Active ingredient description

Naftidrofuryl oxalate is a powerful vasodilator agent with an antagonist effect on 5-HT2 receptors of the smooth muscle cells. The vasodilator effect, which occurs in both the cerebral and peripheral circulation, is probably the main action. It is claimed that this action protects cells against the metabolic effects of ischaemia.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
C04AX21 Naftidrofuryl C Cardiovascular system → C04 Peripheral vasodilators → C04A Peripheral vasodilators → C04AX Other peripheral vasodilators
Discover more medicines within C04AX21

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
NAFTIDROFURYL Capsules Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 31329-57-4
DrugBank Drug: DB13588
RxNorm Ingredient: 7236
SNOMED-CT Concept: 395992001
Naftidrofuryl (substance)
UNII Identifier: 42H8PQ0NMJ
NAFTIDROFURYL

Medicines

Naftidrofuryl is an active ingredient of these brands:

Austria (AT)

Cyprus (CY)

Estonia (EE)

France (FR)

Germany (DE)

Hong Kong (HK)

Ireland (IE)

Singapore (SG)

Spain (ES)

Tunisia (TN)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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