Naphazoline

Chemical formula: C₁₄H₁₄N₂  Molecular mass: 210.274 g/mol  PubChem compound: 4436

Active ingredient description

Naphazoline is a sympathomimetic amine with pronounced alpha adrenergic activity and as a consequence has vasoconstrictor activity.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
R01AA08 Naphazoline R Respiratory system → R01 Nasal preparations → R01A Decongestants and other nasal preparations for topical use → R01AA Sympathomimetics, plain
Discover more medicines within R01AA08
R01AB02 Naphazoline R Respiratory system → R01 Nasal preparations → R01A Decongestants and other nasal preparations for topical use → R01AB Sympathomimetics, combinations excl. corticosteroids
Discover more medicines within R01AB02
S01GA01 Naphazoline S Sensory organs → S01 Ophthalmologicals → S01G Decongestants and antiallergics → S01GA Sympathomimetics used as decongestants
Discover more medicines within S01GA01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
MURINE IRRITATION & REDNESS RELIEF Health Products Regulatory Authority (IE) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 5144-52-5
CAS Substance: 550-99-2
CAS Substance: 835-31-4
DrugBank Drug: DB06711
KEGG Drug: D08253
PubChem Compound: 4436
RxNorm Ingredient: 7247
SNOMED-CT Concept: 372803000
Naphazoline (substance)
UNII Identifier: H231GF11BV
NAPHAZOLINE

Medicines

Naphazoline is an active ingredient of these brands:

Austria (AT)

  • ACONEX as NAPHAZOLINE HYDROCHLORIDE
  • COLDAN as NAPHAZOLINE HYDROCHLORIDE
  • COLDOPHTHAL as NAPHAZOLINE HYDROCHLORIDE
  • RHINON as NAPHAZOLINE HYDROCHLORIDE
  • RHINOPERD as NAPHAZOLINE HYDROCHLORIDE

  • (combination) COLDISTAN as NAPHAZOLINE HYDROCHLORIDE
  • (combination) LUUF as NAPHAZOLINE HYDROCHLORIDE
  • (combination) OPHTAGUTTAL as NAPHAZOLINE HYDROCHLORIDE

Brazil (BR)

  • CLAROFT as NAPHAZOLINE HYDROCHLORIDE
  • MULTISORO ADULTO as NAPHAZOLINE HYDROCHLORIDE
  • NARINEF as NAPHAZOLINE HYDROCHLORIDE
  • NARIX as NAPHAZOLINE HYDROCHLORIDE
  • NASALFLUX as NAPHAZOLINE HYDROCHLORIDE
  • NASOFLUID as NAPHAZOLINE HYDROCHLORIDE
  • NEOSORO as NAPHAZOLINE HYDROCHLORIDE
  • NOVO RINO as NAPHAZOLINE HYDROCHLORIDE
  • NOVOSORO NF as NAPHAZOLINE HYDROCHLORIDE
  • PRIVINA as NAPHAZOLINE NITRATE
  • SONARIN as NAPHAZOLINE HYDROCHLORIDE
  • SOROLIV ADULTO as NAPHAZOLINE HYDROCHLORIDE

  • (combination) CLANISTIL as NAPHAZOLINE HYDROCHLORIDE
  • (combination) CLARIL as NAPHAZOLINE HYDROCHLORIDE
  • (combination) CRISTALIN as NAPHAZOLINE HYDROCHLORIDE
  • (combination) HIDROCIN as NAPHAZOLINE HYDROCHLORIDE
  • (combination) LAVOLHO D as NAPHAZOLINE HYDROCHLORIDE
  • (combination) MAXIBELL as NAPHAZOLINE NITRATE
  • (combination) NARIDRIN as NAPHAZOLINE HYDROCHLORIDE
  • (combination) NEONAZOL as NAPHAZOLINE HYDROCHLORIDE
  • (combination) OCUTIL as NAPHAZOLINE HYDROCHLORIDE
  • (combination) SORINAN as NAPHAZOLINE HYDROCHLORIDE
  • (combination) UNICLARIN as NAPHAZOLINE HYDROCHLORIDE
  • (combination) ZINCOLOK as NAPHAZOLINE HYDROCHLORIDE

Canada (CA)

Croatia (HR)

Cyprus (CY)

  • (combination) OCULOSAN as NAPHAZOLINE NITRATE
  • (combination) SEPTOBORE as NAPHAZOLINE NITRATE
  • (combination) ZABYSEPT as NAPHAZOLINE NITRATE

Ecuador (EC)

France (FR)

  • (combination) DERINOX as NAPHAZOLINE NITRATE

Germany (DE)

Hong Kong (HK)

  • ALBALON as NAPHAZOLINE HYDROCHLORIDE
  • COLDAN as NAPHAZOLINE HYDROCHLORIDE
  • DROPNALIN as NAPHAZOLINE HYDROCHLORIDE
  • NAFTDROP as NAPHAZOLINE HYDROCHLORIDE

  • (combination) COLDISTAN as NAPHAZOLINE HYDROCHLORIDE
  • (combination) DAIGAKU as NAPHAZOLINE HYDROCHLORIDE
  • (combination) FLUCUR as NAPHAZOLINE HYDROCHLORIDE
  • (combination) NAPHCON A as NAPHAZOLINE HYDROCHLORIDE
  • (combination) NASTHOL as NAPHAZOLINE HYDROCHLORIDE
  • (combination) NAZAL as NAPHAZOLINE HYDROCHLORIDE
  • (combination) NAZORIN as NAPHAZOLINE HYDROCHLORIDE
  • (combination) NOSTAMINE as NAPHAZOLINE HYDROCHLORIDE
  • (combination) OCULOSAN as NAPHAZOLINE NITRATE
  • (combination) SUMINE as NAPHAZOLINE HYDROCHLORIDE

Ireland (IE)

Israel (IL)

  • (combination) ALNASE as NAPHAZOLINE HYDROCHLORIDE

Japan (JP)

Lithuania (LT)

  • (combination) COLDISTAN as NAPHAZOLINE HYDROCHLORIDE

Malta (MT)

New Zealand (NZ)

  • ALBALON as NAPHAZOLINE HYDROCHLORIDE
  • NAPHCON as NAPHAZOLINE HYDROCHLORIDE
  • OPTIFIX as NAPHAZOLINE HYDROCHLORIDE
  • OPTREX as NAPHAZOLINE HYDROCHLORIDE

  • (combination) ALBALON-A as NAPHAZOLINE HYDROCHLORIDE
  • (combination) NAPHCON A as NAPHAZOLINE HYDROCHLORIDE
  • (combination) VISINE ALLERGY as NAPHAZOLINE HYDROCHLORIDE

Poland (PL)

Romania (RO)

  • RINOFUG as NAPHAZOLINE HYDROCHLORIDE

  • (combination) BIXTONIM as NAPHAZOLINE HYDROCHLORIDE
  • (combination) NOSTAMINE as NAPHAZOLINE HYDROCHLORIDE

Singapore (SG)

  • (combination) FLUCUR as NAPHAZOLINE HYDROCHLORIDE
  • (combination) NAPHCON A as NAPHAZOLINE HYDROCHLORIDE
  • (combination) NAZAL as NAPHAZOLINE HYDROCHLORIDE

Spain (ES)

Turkey (TR)

  • ENFLUCIDE as NAPHAZOLINE HYDROCHLORIDE

  • (combination) SULFARHIN as NAPHAZOLINE HYDROCHLORIDE

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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