Nebivolol Other names: Nebivolol hydrochloride

Chemical formula: C₂₂H₂₅F₂NO₄  Molecular mass: 405.435 g/mol  PubChem compound: 71301

Active ingredient description

Nebivolol is a racemate of two enantiomers, SRRR-nebivolol (or d-nebivolol) and RSSS-nebivolol (or l-nebivolol). It is a competitive and selective beta-receptor antagonist and it has mild vasodilating properties due to an interaction with the L-arginine/nitric oxide pathway.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
C07AB12 Nebivolol C Cardiovascular system → C07 Beta blocking agents → C07A Beta blocking agents → C07AB Beta blocking agents, selective
Discover more medicines within C07AB12

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
BYSTOLIC Tablet FDA, National Drug Code (US) MPI, US: SPL/PLR
NEBILET Tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 118457-14-0
DrugBank Drug: DB04861
KEGG Drug: D05127
PubChem Compound: 71301
RxNorm Ingredient: 31555
SNOMED-CT Concept: 395808005
Nebivolol (substance)
UNII Identifier: 030Y90569U
NEBIVOLOL

Medicines

Nebivolol is an active ingredient of these brands:

United States (US)

Albania (AL)

Australia (AU)

Austria (AT)

Brazil (BR)

  • BIVOLET as NEBIVOLOL HYDROCHLORIDE
  • LOBEAT as NEBIVOLOL HYDROCHLORIDE
  • LOBIVON as NEBIVOLOL HYDROCHLORIDE
  • NEBIC as NEBIVOLOL HYDROCHLORIDE
  • NEBILET as NEBIVOLOL HYDROCHLORIDE
  • NEBIPRE as NEBIVOLOL HYDROCHLORIDE
  • NEBITAH as NEBIVOLOL HYDROCHLORIDE
  • NEBLOCK as NEBIVOLOL HYDROCHLORIDE
  • TEUBILIV as NEBIVOLOL HYDROCHLORIDE

Canada (CA)

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

  • NEBILOX as NEBIVOLOL HYDROCHLORIDE
  • TEMERIT as NEBIVOLOL HYDROCHLORIDE
  • (combination) CONEBILOX as NEBIVOLOL HYDROCHLORIDE
  • (combination) TEMERITDUO as NEBIVOLOL HYDROCHLORIDE

Germany (DE)

  • NEBILET as NEBIVOLOL HYDROCHLORIDE

Hong Kong (HK)

  • NEBILET as NEBIVOLOL HYDROCHLORIDE

Ireland (IE)

Italy (IT)

  • LOBIVON as NEBIVOLOL HYDROCHLORIDE
  • NEBICARD as NEBIVOLOL HYDROCHLORIDE
  • NEBILOX as NEBIVOLOL HYDROCHLORIDE
  • NEBISCON as NEBIVOLOL HYDROCHLORIDE
  • NIVOLON
  • NOBISTAR as NEBIVOLOL HYDROCHLORIDE
  • (combination) ALONEB as NEBIVOLOL HYDROCHLORIDE
  • (combination) LOBIDIUR as NEBIVOLOL HYDROCHLORIDE
  • (combination) NOBIZIDE as NEBIVOLOL HYDROCHLORIDE

Lithuania (LT)

Malta (MT)

  • NEBILET as NEBIVOLOL HYDROCHLORIDE
  • NEBOL as NEBIVOLOL HYDROCHLORIDE
  • (combination) NEBILET PLUS as NEBIVOLOL HYDROCHLORIDE

Mexico (MX)

  • TEMERIT as NEBIVOLOL HYDROCHLORIDE

Netherlands (NL)

  • NEBILET as NEBIVOLOL HYDROCHLORIDE

Poland (PL)

  • DANEB as NEBIVOLOL HYDROCHLORIDE
  • EBIVOL as NEBIVOLOL HYDROCHLORIDE
  • IVINEB as NEBIVOLOL HYDROCHLORIDE
  • NEBICARD as NEBIVOLOL HYDROCHLORIDE
  • NEBILENIN as NEBIVOLOL HYDROCHLORIDE
  • NEBILET as NEBIVOLOL HYDROCHLORIDE
  • NEBINAD as NEBIVOLOL HYDROCHLORIDE
  • NEBISPES as NEBIVOLOL HYDROCHLORIDE
  • NEBITRIX as NEBIVOLOL HYDROCHLORIDE
  • NEBIVOLEK as NEBIVOLOL HYDROCHLORIDE
  • NEBIVOR as NEBIVOLOL HYDROCHLORIDE
  • NEDAL as NEBIVOLOL HYDROCHLORIDE
  • (combination) NEBILET HCT as NEBIVOLOL HYDROCHLORIDE
  • (combination) TAMANISGA as NEBIVOLOL HYDROCHLORIDE

Romania (RO)

  • NEBILET as NEBIVOLOL HYDROCHLORIDE
  • NOLET as NEBIVOLOL HYDROCHLORIDE
  • (combination) CO-NEBILET as NEBIVOLOL HYDROCHLORIDE

Singapore (SG)

  • NEBILET as NEBIVOLOL HYDROCHLORIDE

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

  • BLOXER as NEBIVOLOL HYDROCHLORIDE
  • CROMTOL as NEBIVOLOL HYDROCHLORIDE
  • NEBINORM as NEBIVOLOL HYDROCHLORIDE
  • NEBIWORLD as NEBIVOLOL HYDROCHLORIDE
  • NEVIMOL as NEBIVOLOL HYDROCHLORIDE
  • NEVOL as NEBIVOLOL HYDROCHLORIDE
  • NEXIVOL as NEBIVOLOL HYDROCHLORIDE
  • VALENDE as NEBIVOLOL HYDROCHLORIDE
  • VASCURA as NEBIVOLOL HYDROCHLORIDE
  • VASOXEN as NEBIVOLOL HYDROCHLORIDE
  • (combination) AMLONEB as NEBIVOLOL HYDROCHLORIDE
  • (combination) NEVIMOL PLUS as NEBIVOLOL HYDROCHLORIDE
  • (combination) VASDAY as NEBIVOLOL HYDROCHLORIDE
  • (combination) VASOXEN PLUS as NEBIVOLOL HYDROCHLORIDE

United Kingdom (UK)

  • NEBILET as NEBIVOLOL HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

 
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