Chemical formula: C₂₇H₄₁F₂N₅O Molecular mass: 489.328 g/mol PubChem compound: 46224413
Nirogacestat is a gamma secretase inhibitor that blocks proteolytic activation of the Notch receptor. When dysregulated, Notch can activate pathways that contribute to tumor growth.
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| OGSIVEO Tablet | FDA, National Drug Code (US) | MPI, US: SPL/PLR |
Nirogacestat is an active ingredient of these brands:
United States (US)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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