Nitisinone

Chemical formula: C₁₄H₁₀F₃NO₅  Molecular mass: 329.228 g/mol  PubChem compound: 115355

Therapeutic indications

Nitisinone is indicated for:

Hereditary tyrosinemia type 1 (HT-1)

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Treatment of adult and paediatric (in any age range) patients with confirmed diagnosis of hereditary tyrosinemia type 1 (HT-1) in combination with dietary restriction of tyrosine and phenylalanine.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Nitisinone is contraindicated in the following cases:

Lactation

Lactation

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