Nystatin

Chemical formula: C₄₇H₇₅NO₁₇  Molecular mass: 926.107 g/mol  PubChem compound: 11953884

Pharmacodynamic properties

Nystatin is an antifungal antibiotic active against a wide range of yeasts and yeast-like fungi, including Candida albicans.

Pharmacokinetic properties

Absorption

Nystatin is formulated in oral and topical dosage forms and is not systemically absorbed from any of these preparations.

Gastrointestinal absorption of nystatin is insignificant.

Elimination

Most orally administered nystatin is passed unchanged in the stool.

Preclinical safety data

No long-term animal studies have been performed to evaluate the carcinogenic potential of nystatin. No studies have been performed to determine the mutagenicity of nystatin or its effect on male or female fertility.

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