Pancreatin when reaching the small intestine disintegrates (at pH>5.5) to release enzymes with lipolytic, amylolytic and proteolytic activity to ensure the digestion of fats, starches and proteins. The products of pancreatic digestion are then either absorbed directly, or following further hydrolysis by intestinal enzymes.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| A09AA02 | Multienzymes (lipase, protease etc.) | A Alimentary tract and metabolism → A09 Digestives, incl. enzymes → A09A Digestives, incl. enzymes → A09AA Diastase |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| CREON Capsule containing gastro-resistant granules | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Pancreatin is an active ingredient of these brands:
United States (US)
Australia (AU)Austria (AT)
Brazil (BR)Canada (CA)
Croatia (HR)Cyprus (CY)Ecuador (EC)
Estonia (EE)
Finland (FI)France (FR)Germany (DE)
Hong Kong (HK)Ireland (IE)Israel (IL)Japan (JP)
Lithuania (LT)Malta (MT)Mexico (MX)Netherlands (NL)
New Zealand (NZ)Poland (PL)
Romania (RO)
Singapore (SG)South Africa (ZA)
Spain (ES)Tunisia (TN)Turkey (TR)
United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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