Paroxetine

Chemical formula: C₁₉H₂₀FNO₃  Molecular mass: 329.365 g/mol  PubChem compound: 43815

Active ingredient description

Paroxetine is a potent and selective inhibitor of 5-hydroxytryptamine (5-HT, serotonin) uptake and its antidepressant action and effectiveness in the treatment of OCD, Social Anxiety disorder/Social Phobia, General Anxiety Disorder, Post-Traumatic Stress Disorder and Panic Disorder is thought to be related to its specific inhibition of 5-HT uptake in brain neurones.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N06AB05 Paroxetine N Nervous system → N06 Psychoanaleptics → N06A Antidepressants → N06AB Selective serotonin reuptake inhibitors
Discover more medicines within N06AB05

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
PAXIL Film‑coated tablet / Oral suspension FDA, National Drug Code (US) MPI, US: SPL/Old
SEROXAT Film-coated tablet / Oral suspension Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 61869-08-7
DrugBank Drug: DB00715
KEGG Drug: D02362
PubChem Compound: 43815
RxNorm Ingredient: 32937
SNOMED-CT Concept: 372595009
Paroxetine (substance)
UNII Identifier: 41VRH5220H
PAROXETINE

Medicines

Paroxetine is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

  • ENNOS as PAROXETINE MESYLATE
  • PAROXAT as PAROXETINE HYDROCHLORIDE
  • SEROXAT as PAROXETINE HYDROCHLORIDE ANHYDROUS

Brazil (BR)

  • AROPAX as PAROXETINE HYDROCHLORIDE
  • CEBRILIN as PAROXETINE HYDROCHLORIDE
  • DEEPLIN as PAROXETINE HYDROCHLORIDE
  • DEPAXAN as PAROXETINE HYDROCHLORIDE
  • MORATUS as PAROXETINE HYDROCHLORIDE
  • PAXIL as PAROXETINE HYDROCHLORIDE
  • PAXTRAT as PAROXETINE HYDROCHLORIDE
  • PONDERA as PAROXETINE HYDROCHLORIDE
  • PRAXETINA as PAROXETINE HYDROCHLORIDE
  • ROXETIN as PAROXETINE HYDROCHLORIDE
  • ZYPAROX as PAROXETINE HYDROCHLORIDE

Canada (CA)

  • PAXIL as PAROXETINE HYDROCHLORIDE

Croatia (HR)

  • SEROXAT as PAROXETINE HYDROCHLORIDE ANHYDROUS

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

  • OPTIPAR as PAROXETINE HYDROCHLORIDE
  • SEROXAT as PAROXETINE HYDROCHLORIDE ANHYDROUS

France (FR)

Germany (DE)

  • PAROXAT as PAROXETINE HYDROCHLORIDE
  • PAROXEDURA as PAROXETINE HYDROCHLORIDE
  • SEROXAT as PAROXETINE HYDROCHLORIDE ANHYDROUS

Hong Kong (HK)

  • DROPAXIN as PAROXETINE HYDROCHLORIDE
  • PAROTIN as PAROXETINE HYDROCHLORIDE
  • SEROXAT as PAROXETINE HYDROCHLORIDE ANHYDROUS
  • SETINE as PAROXETINE HYDROCHLORIDE
  • XALEXA as PAROXETINE HYDROCHLORIDE

Ireland (IE)

  • SEROXAT as PAROXETINE HYDROCHLORIDE ANHYDROUS

Israel (IL)

  • PAROTIN as PAROXETINE HYDROCHLORIDE
  • PAXXET as PAROXETINE HYDROCHLORIDE
  • SEROXAT as PAROXETINE HYDROCHLORIDE ANHYDROUS

Italy (IT)

Japan (JP)

  • PAXIL as PAROXETINE HYDROCHLORIDE

Lithuania (LT)

Malta (MT)

Mexico (MX)

  • CRONADYN as PAROXETINE HYDROCHLORIDE
  • PAXIL as PAROXETINE HYDROCHLORIDE

Netherlands (NL)

  • SEROXAT as PAROXETINE HYDROCHLORIDE ANHYDROUS

New Zealand (NZ)

Poland (PL)

  • ARKETIS
  • DROPAX as PAROXETINE HYDROCHLORIDE
  • PAROGEN as PAROXETINE HYDROCHLORIDE ANHYDROUS
  • PAROXINOR as PAROXETINE HYDROCHLORIDE ANHYDROUS
  • PAXTIN as PAROXETINE HYDROCHLORIDE
  • REXETIN as PAROXETINE HYDROCHLORIDE
  • SEROXAT as PAROXETINE HYDROCHLORIDE ANHYDROUS
  • XETANOR as PAROXETINE HYDROCHLORIDE

Romania (RO)

Singapore (SG)

  • SEROXAT as PAROXETINE HYDROCHLORIDE ANHYDROUS

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

  • SEROXAT as PAROXETINE HYDROCHLORIDE ANHYDROUS

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

 
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