Pasireotide

Chemical formula: C₅₈H₆₆N₁₀O₉  Molecular mass: 1,047.206 g/mol  PubChem compound: 9941444

Active ingredient description

Pasireotide is a novel cyclohexapeptide, injectable somatostatin analogue. Pasireotide exerts its pharmacological activity via binding to somatostatin receptors. Somatostatin receptors are expressed in many tissues, especially in neuroendocrine tumours in which hormones are excessively secreted, including ACTH in Cushing’s disease.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
H01CB05 Pasireotide H Systemic hormonal preparations, excl. Sex hormones and insulins → H01 Pituitary and hypothalamic hormones and analogues → H01C Hypothalamic hormones → H01CB Somatostatin and analogues
Discover more medicines within H01CB05

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
SIGNIFOR Solution for injection European Medicines Agency (EU) MPI, EU: SmPC
SIGNIFOR Powder and solvent for suspension for injection European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 396091-73-9
DrugBank Drug: DB06663
KEGG Drug: D10147
PubChem Compound: 9941444
RxNorm Ingredient: 1364105
SNOMED-CT Concept: 704266003
Pasireotide (substance)
UNII Identifier: 98H1T17066
PASIREOTIDE

© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.