Pegvisomant

Active ingredient description

Pegvisomant is an analogue of human growth hormone that has been genetically modified to be a growth hormone receptor antagonist for the treatment of adult patients with acromegaly. Pegvisomant is highly selective for the GH receptor, and does not cross-react with other cytokine receptors, including prolactin.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
H01AX01 Pegvisomant H Systemic hormonal preparations, excl. Sex hormones and insulins → H01 Pituitary and hypothalamic hormones and analogues → H01A Anterior pituitary lobe hormones and analogues → H01AX Other anterior pituitary lobe hormones and analogues
Discover more medicines within H01AX01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
SOMAVERT Powder and solvent for solution for injection European Medicines Agency (EU) MPI, EU: SmPC

External identifiers

CAS Substance: 218620-50-9
DrugBank Drug: DB00082
RxNorm Ingredient: 278739
SNOMED-CT Concept: 409201000
Pegvisomant (substance)
UNII Identifier: N824AOU5XV
PEGVISOMANT

Medicines

Pegvisomant is an active ingredient of these brands:

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

Estonia (EE)

Finland (FI)

France (FR)

Ireland (IE)

Israel (IL)

Italy (IT)

Japan (JP)

Lithuania (LT)

Netherlands (NL)

Poland (PL)

Romania (RO)

Spain (ES)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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