Phenylpropanolamine Other names: β-hydroxyamphetamine

Molecular mass: 151.209 g/mol  PubChem compound: 26934

Active ingredient description

Phenylpropanolamine is a sympathomimetic agent which is used as a decongestant and appetite suppressant. It was commonly used in prescription and over-the-counter cough and cold preparations. Although originally thought to act as a direct agonist of adrenergic receptors, phenylpropanolamine was subsequently found to show only weak or negligible affinity for these receptors, and has been instead characterized as an indirect sympathomimetic which acts by inducing norepinephrine release and thereby activating adrenergic receptors.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
R01BA01 Phenylpropanolamine R Respiratory system → R01 Nasal preparations → R01B Nasal decongestants for systemic use → R01BA Sympathomimetics
Discover more medicines within R01BA01

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 14838-15-4
DrugBank Drug: DB00397
PubChem Compound: 26934
RxNorm Ingredient: 8175
SNOMED-CT Concept: 387464001
Phenylpropanolamine (substance)
UNII Identifier: 33RU150WUN
PHENYLPROPANOLAMINE

Medicines

Phenylpropanolamine is an active ingredient of these brands:

Finland (FI)

  • RINEXIN as PHENYLPROPANOLAMINE HYDROCHLORIDE

Hong Kong (HK)

  • (combination) DIMAXIN as PHENYLPROPANOLAMINE HYDROCHLORIDE
  • (combination) DIMEFORT as PHENYLPROPANOLAMINE HYDROCHLORIDE
  • (combination) EASCOLD as PHENYLPROPANOLAMINE HYDROCHLORIDE
  • (combination) EUROCOSYN as PHENYLPROPANOLAMINE HYDROCHLORIDE
  • (combination) EUROTAPP as PHENYLPROPANOLAMINE HYDROCHLORIDE
  • (combination) FLUDANE as PHENYLPROPANOLAMINE HYDROCHLORIDE
  • (combination) KOSYPHAN as PHENYLPROPANOLAMINE HYDROCHLORIDE
  • (combination) NEOZEP COLD as PHENYLPROPANOLAMINE HYDROCHLORIDE
  • (combination) NORSETOA as PHENYLPROPANOLAMINE HYDROCHLORIDE
  • (combination) PHOLCOLIN as PHENYLPROPANOLAMINE HYDROCHLORIDE
  • (combination) SYNCOLDTAB-M as PHENYLPROPANOLAMINE HYDROCHLORIDE
  • (combination) UNI-VASIN as PHENYLPROPANOLAMINE HYDROCHLORIDE

South Africa (ZA)

  • (combination) ALLEREST as PHENYLPROPANOLAMINE HYDROCHLORIDE
  • (combination) BETALIX as PHENYLPROPANOLAMINE HYDROCHLORIDE
  • (combination) DEGORAN L as PHENYLPROPANOLAMINE HYDROCHLORIDE
  • (combination) DEGORAN T as PHENYLPROPANOLAMINE HYDROCHLORIDE
  • (combination) DIMUCON as PHENYLPROPANOLAMINE HYDROCHLORIDE
  • (combination) NITECALL as PHENYLPROPANOLAMINE HYDROCHLORIDE
  • (combination) ORNACOL as PHENYLPROPANOLAMINE HYDROCHLORIDE
  • (combination) RINEX as PHENYLPROPANOLAMINE HYDROCHLORIDE
  • (combination) SINUCLEAR as PHENYLPROPANOLAMINE HYDROCHLORIDE
  • (combination) SINUSTAT as PHENYLPROPANOLAMINE HYDROCHLORIDE

Turkey (TR)

  • (combination) CORSAL as PHENYLPROPANOLAMINE HYDROCHLORIDE
  • (combination) GLIFENTOL
  • (combination) NOVENTA as PHENYLPROPANOLAMINE HYDROCHLORIDE
  • (combination) TUSEPTIL as PHENYLPROPANOLAMINE HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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