Phosphorus

Chemical formula:Molecular mass: 30.974 g/mol 

Pharmacodynamic properties

Phosphate plays important roles in the osteoblastic and osteoclastic reactions. It interacts with calcium to modify the balance between these two processes. Organic phosphate esters play a key role in the metabolism of carbohydrates, fats and proteins and in the formation of ‘high energy phosphate’ compounds. Phosphate also acts as a buffer and plays a role in the renal excretion of sodium and hydrogen ions.

Pharmacokinetic properties

The body contains from 600-800 g of phosphorus, over 80% of which is present in the bone as phosphate salts, mainly hydroxyapatite crystals. The phosphate in these crystals is available for exchange with phosphate ions in the extra-cellular fluids.

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