Physostigmine Other names: Eserolein methylcarbamate Eserine Eserine sulfate Erserine

Chemical formula: C₁₅H₂₁N₃O₂  Molecular mass: 275.346 g/mol  PubChem compound: 5983

Active ingredient description

Physostigmine is a reversible inhibitor of acetylcholinesterase. As an inhibitor of acetyl-cholinesterase, physostigmine slows down the degradation of acetylcholine and acts like an indirect parasympathomimetic drug due to an increase of the acetylcholine concentration at the receptor.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
S01EB05 Physostigmine S Sensory organs → S01 Ophthalmologicals → S01E Antiglaucoma preparations and miotics → S01EB Parasympathomimetics
Discover more medicines within S01EB05
V03AB19 Physostigmine V Various → V03 All other therapeutic products → V03A All other therapeutic products → V03AB Antidotes
Discover more medicines within V03AB19

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
ANTICHOLIUM Injection solution MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 57-47-6
DrugBank Drug: DB00981
KEGG Drug: D00196
PubChem Compound: 5983
RxNorm Ingredient: 8299
SNOMED-CT Concept: 373347005
Physostigmine (substance)
UNII Identifier: 9U1VM840SP
PHYSOSTIGMINE

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