Chemical formula: C₁₃H₁₉NO₄S Molecular mass: 285.359 g/mol PubChem compound: 4911
Probenecid is a uricosuric and renal tubular blocking agent. It inhibits the tubular reabsorption of urate, thus increasing the urinary excretion of uric acid and decreasing serum urate levels. Effective uricosuria reduces the miscible urate pool, retards urate deposition, and promotes resorption of urate deposits.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| M04AB01 | Probenecid | M Musculo-skeletal system → M04 Antigout preparations → M04A Antigout preparations → M04AB Preparations increasing uric acid excretion |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| PROBENECID Film-coated tablet | FDA, National Drug Code (US) | MPI, US: SPL/Old | |
| PROBENECID-AFT Film coated tablet | Medicines and Medical Devices Safety Authority (NZ) | MPI, EU: SmPC |
Probenecid is an active ingredient of these brands:
Australia (AU)France (FR)Japan (JP)Mexico (MX)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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