Chemical formula: C₁₃H₂₀N₂O₂ Molecular mass: 236.31 g/mol PubChem compound: 4914
Procaine is a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. In addition, this agent increases electrical excitation threshold, reduces rate of rise of action potential and slows nerve impulse propagation thereby causing loss of sensation. Procaine is indicated for production of local or regional anesthesia, particularly for oral surgery. Procaine (like cocaine) has the advantage of constricting blood vessels which reduces bleeding, unlike other local anesthetics like lidocaine.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C05AD05 | Procaine | C Cardiovascular system → C05 Vasoprotectives → C05A Agents for treatment of hemorrhoids and anal fissures for topical use → C05AD Local anesthetics |
| N01BA02 | Procaine | N Nervous system → N01 Anesthetics → N01B Anesthetics, local → N01BA Esters of aminobenzoic acid |
| S01HA05 | Procaine | S Sensory organs → S01 Ophthalmologicals → S01H Local anesthetics → S01HA Local anesthetics |
Procaine is an active ingredient of these brands:
Austria (AT)
Brazil (BR)France (FR)
Singapore (SG)
Turkey (TR)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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